Contrave is a combination of two active ingredients: bupropion and naltrexone. Bupropion is an antidepressant medication that tapers one’s appetite. Naltrexone is a medication used to treat addictions (and can also reduce the patient’s food cravings).
This medication is FDA-approved for patients with a BMI of 30 or higher or a BMI of 27 or higher with a condition related to their weight. The treatment is most effective when combined with a healthy lifestyle.
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Plenity works by expanding the stomach and small intestine, making the patient feel full and reducing their appetite. This treatment is approved for patients with a body mass index of 25 to 40 and struggling to lose weight.
Multiple clinical studies have found that Plenity effectively achieves weight loss over time. One clinical trial found that, on average, patients who took Plenity saw a 6.4% reduction in body weight, while the placebo group only had a reduction of 4.4%.
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Zepbound is a tirzepatide injection that operates by targeting certain chemicals in your brain that regulate appetite. When you take Zepbound, it acts to suppress your hunger, which can lead to a reduced calorie intake. It's important to note that Zepbound is most effective when you also adhere to a healthy eating plan and stay active.
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